Abstract

Purpose: Preeclampsia affects 2% to 8% of pregnancies and is a significant complication that manifests in the second or third trimester with potential adverse outcomes for both mothers and fetuses. The study aims to assess the diagnostic utility of NLR and PLR, between 12-16 weeks of POG to predict the development of preeclampsia. Material and Methods: This prospective case- control study was conducted from January 2019 to January 2022. We included 100 pregnant women, aged between 18-40 years and at less than 16 weeks POG. CBC including hemoglobin, differential leukocyte counts and their ratio NLR and PLR for all patients at 12-16 weeks were measured. All pregnant women were followed till delivery to see development of preeclampsia. We used a receiver operating characteristic curve to evaluate the cutoff, sensitivity, and specificity values. Results: The study enrolled 100 age and gestation matched pregnant women, out of them 30 developed preeclampsia. Mean age and gestational age were comparable within groups. The BMI (27.05±4.49, 23.96±3.5, p